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Image Search Results


Characteristics of the studied cohorts.

Journal: PLoS ONE

Article Title: LTA4H rs2660845 association with montelukast response in early and late-onset asthma

doi: 10.1371/journal.pone.0257396

Figure Lengend Snippet: Characteristics of the studied cohorts.

Article Snippet: In this study, we utilised a very large dataset, consisting of previously described, ethnically diverse case-control studies (GALA II and SAGE), asthma cohorts (BREATHE and PAGES), a randomised clinical trial (RCT) (Tayside RCT) and two large real-life cohorts (the UKBiobank and GoSHARE), to explore the association of rs2660845 with lack of montelukast treatment response.

Techniques: Variant Assay

Association of exacerbation under montelukast treatment with rs2660845 genotype.

Journal: PLoS ONE

Article Title: LTA4H rs2660845 association with montelukast response in early and late-onset asthma

doi: 10.1371/journal.pone.0257396

Figure Lengend Snippet: Association of exacerbation under montelukast treatment with rs2660845 genotype.

Article Snippet: In this study, we utilised a very large dataset, consisting of previously described, ethnically diverse case-control studies (GALA II and SAGE), asthma cohorts (BREATHE and PAGES), a randomised clinical trial (RCT) (Tayside RCT) and two large real-life cohorts (the UKBiobank and GoSHARE), to explore the association of rs2660845 with lack of montelukast treatment response.

Techniques:

Summary of selected therapeutic strategies targeting the cytokine storm in COVID-19 in phase 3 and 4 clinical trials registered on clinicaltrials.gov and clinicaltrialsregister.eu databases Abbreviations: SOC, standard of care; IMV, invasive mechanical ventilation; MV, mechanical ventilation; ICU, intensive care unit; ECMO, extracorporeal membrane oxygenation.

Journal: Biomolecules

Article Title: Cytokines and Chemokines in SARS-CoV-2 Infections—Therapeutic Strategies Targeting Cytokine Storm

doi: 10.3390/biom11010091

Figure Lengend Snippet: Summary of selected therapeutic strategies targeting the cytokine storm in COVID-19 in phase 3 and 4 clinical trials registered on clinicaltrials.gov and clinicaltrialsregister.eu databases Abbreviations: SOC, standard of care; IMV, invasive mechanical ventilation; MV, mechanical ventilation; ICU, intensive care unit; ECMO, extracorporeal membrane oxygenation.

Article Snippet: Infliximab is currently tested in a randomised phase 3 clinical trial among other immune-modulating candidates for treating COVID-19 as an add-on therapy to the already approved remdesivir (Gilead Sciences, Inc., Foster City, CA, USA) (NCT04593940).

Techniques: Injection, Variant Assay